Other Solvents
Medchemexpress LLC 4-fluoronitrobenzene-d4 | 1219802-01-3 | 50mg
NSC 10281-d4 is the deuterium labeled NSC 10281[1]
Medchemexpress LLC 2,4(1H,3H)-Pyrimidinedione-6-d, 5-(methyl-d3)- | 200496-79-3 | 98% | 130.14 | 25 MG
Thymine-d4 is the deuterium labeled Thymine, one of the four nucleobases in the nucleic acid of DNA. It can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules as tracers for quantitation during drug development. Deuteration, in particular, has potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC (Rac)-Bedaquiline-d6 | 2517573-53-2 | 99.0% | 561.54 | 5 MG
(Rac)-Bedaquiline-d6 is the deuterium labeled Bedaquiline. It is a diarylquinoline agent that inhibits *Mycobacterium tuberculosis* (Mtb) F1FO-ATP synthase by targeting both the c- and the ε-subunit. This compound exhibits uncoupler activity and is used for multi-agent resistant tuberculosis.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
![eMolecules 74362-46-2 | Imidazole-15N2 | Toronto Research Chemicals | MFCD00144471 | 70.065 | C3H4N2c1c[15nH]c[15n]1 | 100mg | 483415951](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502175462.JPG-250.jpg)
eMolecules 74362-46-2 | Imidazole-15N2 | Toronto Research Chemicals | MFCD00144471 | 70.065 | C3H4N2c1c[15nH]c[15n]1 | 100mg | 483415951
Imidazole-15N2 | Toronto Research Chemicals | 74362-46-2 | MFCD00144471 | 70.065 | C3H4N2c1c[15nH]c[15n]1 | 100mg | 483415951
Medchemexpress LLC Sucrose-d14 | 99.0% | 5 MG
Sucrose-d14 is the deuterium labeled Sucrose. Sucrose (D-(+)-Saccharose) is a disaccharide composed of two monosaccharides, glucose and fructose. It can be applied in animal models for metabolic disease, obesity, and diet preference studies.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, primarily as tracers for quantitation during drug development.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Umbelliferone-d5 | 1215373-23-1 | 167.17 | 2.5 MG
Umbelliferone-d5 (7-Hydroxycoumarin-d5) is a deuterium-labeled coumarin derivative, a natural and orally active compound. It is a fluorescing agent and has shown diverse biological activities including anticancer, anti-inflammatory, and neuroprotective effects. This compound serves as a valuable tool for quantitative analysis in research.
- Deuterium-labeled for quantitative analysis
- Can be used as a tracer in drug development
- Acts as an internal standard for techniques like NMR, GC-MS, or LC-MS
- Exhibits anticancer effects by inducing cell cycle arrest and apoptosis
- Attenuates allergic airway inflammation
- Displays neuroprotective, anti-inflammatory, and antioxidant properties
Medchemexpress LLC Valacyclovir-d8 (hydrochloride) | 1279033-32-7 | 98.0% | 368.85 | 5 MG
Valacyclovir-d8 hydrochloride is a deuterium-labeled, orally active antiviral agent. It is effective against herpes simplex, herpes zoster, and herpes B, and acts as a proagent of Aciclovir.
- Deuterium labeled for use as a tracer or internal standard for quantitative analysis.
- Orally active antiviral agent effective for herpes simplex, herpes zoster, and herpes B.
- Inhibits HSV-1 W with an IC50 of 2.9 μg/ml.
- Proagent of Aciclovir.
Medchemexpress LLC L-Asparagine-15N2 hydrate | 287484-32-6 | 152.12 | 50 MG
L-Asparagine-15N2 monohydrate is the 15N-labeled L-Asparagine monohydrate. It is an essential amino acid for leukemic cells and a substrate for L-Asparaginase, a potent anti-leukemic enzyme. L-Asparaginase promotes asparagine and glutamine depletion, inhibiting protein biosynthesis in lymphoblasts, leading to inhibition of RNA and DNA synthesis and subsequent apoptosis. This compound can be used as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Used as a tracer
- Used as an internal standard for quantitative analysis
- Suitable for NMR, GC-MS, or LC-MS applications
![Revvity Health Sciences Inc Prazosin, [7-Methoxy-<sup>3</sup>H]-, 250µCi (9.25MBq)](https://assets.fishersci.com/TFS-Assets/CCG/product-images/509051070.jpg-250.jpg)
Revvity Health Sciences Inc Prazosin, [7-Methoxy-3H]-, 250µCi (9.25MBq)
Prazosin, [7-Methoxy-3H]-, 250µCi (9.25MBq)
Medchemexpress LLC Febuxostat-d9 | 1246819-50-0 | MFCD21363615 | 98.7% | C16H7D9N2O3S | 10MG
Febuxostat-d9 is a deuterium-labeled analogue of febuxostat supplied as an isotopically labeled reference standard for analytical and research applications. It is intended for use as an internal standard in LC- or GC-MS assays and in studies of xanthine oxidase inhibition. The material is supplied with high isotopic enrichment and high chemical purity (≈98.7%, C16H7D9N2O3S, MW 325.43) for research use only.
- Deuterium-labeled internal standard for LC- or GC-MS quantification.
- Facilitates accurate quantification and compensation for matrix effects.
- High isotopic enrichment and purity for reliable analytical performance.
- Suitable for pharmacokinetic, metabolic, and bioanalytical studies.
- Provides a clear mass shift from the unlabeled analyte for MS separation.
Medchemexpress LLC Salbutamol-d9 | 1173021-73-2 | 98.0% | 1 MG
Salbutamol-d9 (Albuterol-d9) is a deuterium-labeled short-acting β2-adrenergic receptor agonist. It serves as a tracer and internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS. The unlabeled compound, Salbutamol, is known to promote tumorigenesis in gastric cancer cells via the β2-AR/ERK/EMT pathway and can relax bronchial smooth muscle, which is pertinent for studies concerning bronchospasm related to asthma and chronic obstructive pulmonary disease.
- Deuterium-labeled compound for research applications.
- Functions as a tracer for quantitative analysis.
- Can be used as an internal standard in analytical methods.
- Supports research in areas like asthma and chronic obstructive pulmonary disease.
- Relevant for studies on tumorigenesis in gastric cancer cells.
![Revvity Health Sciences Inc Dehydroepiandrosterone Sulfate, Sodium Salt, [1,2,6,7-<sup>3</sup>H(N)]-, 250µCi (9.25MBq)](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502812748.jpg-250.jpg)
Revvity Health Sciences Inc Dehydroepiandrosterone Sulfate, Sodium Salt, [1,2,6,7-3H(N)]-, 250µCi (9.25MBq)
Dehydroepiandrosterone Sulfate, Sodium Salt, [1,2,6,7-3H(N)]-, 250µCi (9.25MBq)